Dr. V. Barbakadze - Head of the Laboratory of Plant Biopolymers
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Tbilisi State Medical University I.Kutateladze Institute of Pharmacochemistry

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Dr. V.Barbakadze

 

 

 

 

Dr. Vakhtang Barbakadze

 

Head of the Laboratory of Plant Biopolymers

 
     
Date and place of Birth:   Georgia, March 28, 1945  

 

MAIN FIELDS OF ACTIVITIES

 

Chemistry and Biochemistry of Natural Products, Plant Polysaccharides, Plant Macromolecules.

 

EDUCATIONAL BACKGROUND

1962-1968 - Graduated from Georgian Polytechnical Institute, Faculty of Chemical & Food Technology, Tbilisi, Georgia.

 

1974-1978 - Post-graduate student. Zelinsky Instiute of Organic Chemistry, Moscow, Russia.

 

1978 - Ph.D. (candidate of chemical sciences), Zelinsky Instiute of Organic Chemistry, Moscow, Russia.

 

1999 - D.Sci. (doctor of biological sciences), Durmishidze Institute of Biochemistry and Biotechnology, Tbilisi, Georgia.

 

INSTITUTIONAL AFFILIATION

08.2006 – up to date - Head of Laboratory of Plant Biopolymers, Kutateladze Institute of Pharmacochemistry (KIP).

 

2000 – 08.2006 - Principal Research Scientist, KIP, Tbilisi, Georgia.

 

1989-1999 - Senior Research Scientist (KIP), Tbilisi, Georgia.

 

1985-1988 - Senior Research Scientist, Tbilisi State University, Department of Chemistry.

 

1982-1984 - Chief Expert of Chemical Sciences & Technology, State Committee of Sciences & Technology, Tbilisi, Georgia.

 

1978-1981 - Senior Research Scientist, Institute of Plant Biochemistry (IPB), Tbilisi, Georgia.

 

1969-1973 - Junior Research Scientist. IPB, Tbilisi, Georgia.

 

1996 - Visiting Scientist, Utrecht University Scholarship, Faculty of Pharmacy, Department of Pharmacognosy, The Netherlands.

 

2002 - Visiting Scientist, NWO Scientific Program, Utrecht University, Faculty of Pharmacy, Department of Medicinal Chemistry, The Netherlands.

 

PUBLICATIONS

 

64 scientific publications.

 

RECENT

PUBLICATIONS

 

1.      M.Merlani, V.Barbakadze, L.Amiranashvili, L.Gogilashvili, E.Yannakopoulou, K.Papadopoulos, B.Chankvetadze. Enantioselective synthesis and antioxidant activity of 3-(3,4-dihydroxyphenyl)-glyceric acid - Basic monomeric moiety of a biologically active polyether from Symphytum asperum and S. caucasicum. Chirality, 2010, V. 22, N 8, P. 717-725.
2. V.Barbakadze,  L.Gogilashvili,  L.Amiranashvili,  M.Merlani,  K.Mulkijanyan,  M.Churadze,  A.Salgado,  B.Chankvetadze. Poly[3-(3,4-dihydroxyphenyl)glyceric acid] from Anchusa italica roots. Natural Product Communications, 2010, V. 5, N 7, P.1091-1095.
3. V. V. Barbakadze,  K. G. Mulkidzhanyan,  M. I. Merlani,  L. M. Gogilashvili, L. Sh. Amiranashvili,  E. K. Shaburishvili. Extraction, composition and the antioxidant and anticomplement activities of high molecular weight fractions from the leaves of Symphytum asperum and S.caucasicum. Pharm. Chem. J., 2011, Vol. 44, No. 11, P.604-607.
http://www.springerlink.com/content/91t670085537311t/

 4. V.Barbakadze,  L.Gogilashvili,  L. Amiranashvili,  M. Merlani,  K. Mulkijanyan. Spectrophotomertric quantitative determination of poly[3-(3,4-dihydroxyphenyl)glyceric acid]. Bull. Georg. Natl. Acad. Sci. 2010, V. 4, N 3, P. 123-126.
bulletin@science.org.ge
5. V.Barbakadze. Anti-cancer efficacy of novel phenolic polymer from Symphytum asperum and S.caucasicum (Boraginaceae) against androgen-dependent and -independent human prostate cancer cells. J. Anal. Bioanal. Techniques. 2011, V. 2, N 6, P. 46.
http://www.omicsonline.org/ArchiveJABT.php
6. M.Merlani, V.Barbakadze, L.Amiranashvili, L. Gogilashvili, K. Mulkijanyan. Synthesis of Some Caffeic and 2,3-Dihydroxy-3-(3,4-Dihydroxyphenyl)-Propanoic Acids Amides. Bull. Georg. Natl. Acad. Sci. 2011, V. 5, N 3, P. 107-111.Bull. Georg. Nat.org.ge
7. V.Barbakadze, K.Mulkjanyan, L.Gogilashvili, M.Merlani, L.Amiranashvili, Zh.Novikova, M.Sulakvelidze. Sum of high-molecular compounds of comfrey roots and its use for treatment. National Intellectual Property Center of Georgia “SAKPATENTI”. Official Bulletin of the Industrial Property 2 (342). Inventions, Utility Models, Designs, Trademarks. 25 January 2012. Patent P 5391 Invention.

 8. K.Lomsadze, M.Merlani, V.Barbakadze, T.Farkas, B. Chankvetadze. Enantioseparation of Chiral Epoxides with Polysaccharide-Based Chiral Columns in HPLC. Chromatographia, 2012, V. 75, N 15-16, P. 839-845. http://www.springerlink.com/content/g47294x10t19/

9. V.Barbakadze, L.Gogilashvili, L.Amiranashvili, M.Merlani, K.Mulkjanyan, A.Salgado, B.Chankvetadze. Novel biologically active dihydroxycinnamate-derived polyether from different species of Boraginaceae family. XXVIth International Conference on Polyphenols. Polyphenols Communications 2012. 2012, V. I, P. 57-58.
10.  S.Shrotriya, G.Deep, K.Ramasamy, K.Raina, V.Barbakadze, M.Merlani, L. Gogilashvili, L.Amiranashvili, K.Mulkijanyan, K.Papadopoulos, C.Agarwal, R.Agarwal. Poly[3-(3, 4-dihydroxyphenyl) glyceric] acid from comfrey exerts anti-cancer efficacy against human prostate cancer via targeting androgen receptor, cell cycle arrest and apoptosis. Carcinogenesis. 2012, V. 33, N 8, P. 1572-1580.
http://carcin.oxfordjournals.org/content/33/8.toc
11.  V.Barbakadze, M.Merlani, L.Amiranashvili, L.Gogilashvili, K.Mulkijanyan. Study of Poly[Oxy-1-Carboxy-2-(3,4-Dihydroxyphenyl)Ethylene] From Symphytum asperum, S.caucasicum, S.officinale, Anchusa italica by Circular Dichroism. Bull. Georg. Natl. Acad. Sci. 2012, V. 6, N 1, P. 143-146.
http://www.science.org.ge/ 
12.  V.Barbakadze, L.Gogilashvili, L. Amiranashvili, M. Merlani, K. Mulkijanyan, S.Gokadze, Y.Wang, J.Hoang,  I.Rustamov. HPLC analysis of poly[3-(3,4-dihydroxyphenyl)glyceric acid] preparations from Symphytum asperum and Anchusa italica (Boraginaceae) using different gel-filtration columns. Bull. Georg. Natl. Acad. Sci. 2013, V. 7, N 1, P. 83-88.
http://www.science.org.ge/ 
13.  S. Gokadze, V. Barbakadze, L. Gogilashvili, L. Amiranashvili, A. Bakuridze. Development of technology for the substance of poly[3-(3,4-dihydroxyphenyl) glyceric Acid] from Symphytum asperum. Georgian Med News. 2013, V. 218, P. 72-77. (in Russian).
14.  V.Barbakadze, L.Gogilashvili, L.Amiranashvili, M.Merlani, K. Mulkijanyan, A.Salgado, B.Chankvetadze. Novel biologically active dihydroxycinnamate-derived polyether from different species of family Boraginaceae. Bull. Georg. Natl. Acad. Sci. 2013, V. 7, N 2, P. 136-142.
http://www.science.org.ge/  

 

 

LANGUAGES

 English, Russian, Georgian.

 

AWARDS

2004 – Georgian State Prize Winner in Science and Technology

 

CONTACT

INFORMATION

office: * Kutateladze Institute of  Pharmacochemistry, 36 P.Sarajishvili Street, Tbilisi, 0159, Georgia

(: +995-32 532 170  fax: +995-32 520 023;

e-mail: vbarbakadze@gmail.com;

           v_barbakadze@hotmail.com

home: * 21 Kekelidze Street, apt. 41, Tbilisi, 0179, Georgia

(+995-32) 232 026; (+995-55) 531 509         

    

 

ADDITIONAL INFORMATION

Nationality: Georgian

Marital status: married – wife Iraida Targamadze

Children: daughter  – Tamara Barbakadze

N. Gorgaslidze

Director of the I.Kutateladze Institute of Pharmacochemistry

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Z. Antelidze

Financial Director

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E. Kemertelidze

Member of the Georgian National Academy of Sciences,

Head of the Laboratory of Steroids and Cardiac Glycosides

Member of the Academic Council of the Institute

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G. Tsagareishvili

Head of the Laboratory of Pharmaceutical Technology,

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G. Dekanosidze

Head of the Laboratory of Triterpene Compounds

Member of the Academic Council of the Institute

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V. Vachnadze.

Head of the Laboratory of Alkaloids

Member of the Academic Council of the Institute

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M. Alania

Head of the Laboratory of Phenolic Compounds

Member of the Academic Council of the Institute

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V. Barbakadze

Head of the Laboratory of Plant Biopolymers

Member of the Academic Council of the Institute

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D. Turabelidze

Head of the Laboratory of Lipids and Anthraquinons

Member of the Academic Council of the Institute

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G. Erkomaishvili

Head of the Laboratory of Fermentology

Member of the Academic Council of the Institute

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P. Iavich

Head of the Laboratory of Pharmaceutical Analysis

Member of the Academic Council of the Institute

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M. Churadze (Tshuradze)

Head of the Laboratory of Pharmacobotany

Member of the Academic Council of the Institute

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L. Kincurashvili

Senior Research Scientist, Laboratory of Alkaloids

Secretary of the Academic Council of the Institute

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M. Merlani

Senior Research Scientist, Laboratory of Plant Biopolymers

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V. Mshvildadze

Senior research  scientist, Laboratory of Triterpenoids

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L. Gvazava

Senior Research Scientist, Laboratory of Steroids and Cardiac Glycosides

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N. Nadaraia

Principal Research Scientist, Laboratory of Chemical Modification of Natural Compounds

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K. Mchedlidze

Senior Research Scientist, Laboratory of Pharmacobotany

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L. Nadiraishvili

Senior research scientist,  Laboratory of Fermentology

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Ts. Sulakvelidze

Senior research scientist, Laboratory of Lipids and Anthraquinones

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T. Suladze

Research scientist, Laboratory of Alkaloids

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N. Vachnadze

Research scientist, Laboratory of Alkaloids

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M. Getia

Research  scientist, Laboratory of Triterpene Compounds

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B. Tabidze

Research  scientist, Laboratory of Triterpenoids

Member of the Academic Council of the Institute

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T. Sagareishvili

Senior research  scientist, Laboratory of Phenolic Compounds

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N. Kavtaradze

Research  scientist, Laboratory of Phenolic Compounds

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M. Benidze

Senior research  scientist, Laboratory of Steroids and Cardiac Glycosides

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A. Skhirtladze

Research  scientist, Laboratory of Steroids and Cardiac Glycosides

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T. Muzashvili

Research  scientist, Laboratory of Steroids and Cardiac Glycosides

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L. Gogilashvili

Senior Research Scientist, Laboratory of Plant Biopolymers

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L. Amiranashvili
Research  scientist, Laboratory of Plant Biopolymers

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L.Churadze

Research  scientist, Laboratory of Pharmaceutical Analysis

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L. Tsiklauri

Senior research  scientist, Laboratory of  Pharmaceutical Technology 

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M. Orjonikidze

Research  scientist, Laboratory of Pharmaceutical Technology 

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M. Kakhabrishvili

Senior research  scientist, Laboratory of Chemical Modification of Natural Compounds

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J. Aneli

Research  scientist, Laboratory of Pharmacobotany

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D. Chanturia

Research  scientist, Laboratory of Fermentology

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B. Kikalishvili

Research  scientist, Laboratory of Lipids and Anthraquinones  

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K. Mulkijanyan

Head of the Department of Pharmacology

Member of the Representative Council of the Tbilisi State Medical University

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N. Gogitidze

Research Scientist, Department of  Pharmacology...

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M. Moistsrapishvili

Assistant researcher, Department of Pharmacology

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N. Mushkiashvili

Research Scientist, Department of  Pharmacology

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Zh. Novikova

Research Scientist, Department of  Pharmacology...

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M. Sulakvelidze

Senior Research Scientist, Department of  Pharmacology...

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M. Khvedelidze

Analyst

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N. Barbakadze

Research Scientist, Laboratory of Chemical Modification of Natural Compounds

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M. Sutiashvili

Research Scientist, Laboratory of Phenolic Compounds

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K. Shalashvili

Senior research scientist

Laboratory of Phenolic Compounds

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M. Malania

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Z. Kemoklidze

Z. Kemoklidze

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